| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Hemogen (419-469) is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:1000-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | HEMGN |
| Gene ID: | 55363 |
| Uniprot ID: | HEMGN_HUMAN |
| Immunogen Region: | 419-469 |
| Specificity: | This antibody detects endogenous levels of human HEMGN |
| Immunogen: | Synthesized peptide derived from human HEMGN AA range: 419-469 |
| Function | Regulates the proliferation and differentiation of hematopoietic cells. Overexpression block the TPA-induced megakaryocytic differentiation in the K562 cell model. May also prevent cell apoptosis through the activation of the nuclear factor-kappa B (NF-kB). |
| Protein Name | Hemogen Erythroid Differentiation-Associated Gene Protein Edag-1 Hemopoietic Gene Protein Negative Differentiation Regulator Protein |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Hemogen antibody Anti-Erythroid Differentiation-Associated Gene Protein antibody Anti-Edag-1 antibody Anti-Hemopoietic Gene Protein antibody Anti-Negative Differentiation Regulator Protein antibody Anti-HEMGN antibody Anti-EDAG antibody Anti-NDR antibody Anti-PRO1037 antibody Anti-PRO1620 antibody |
Information sourced from Uniprot.org