| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: | HELZ |
| Gene ID: | 9931 |
| Uniprot ID: | HELZ_HUMAN |
| Immunogen Region: | 1-102 aa |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-102 of human HELZ (NP_055692.2). |
| Immunogen Sequence: | MEDRRAEKSCEQACESLKRQ DYEMALKHCTEALLSLGQYS MADFTGPCPLEIERIKIESL LYRIASFLQLKNYVQADEDC RHVLGEGLAKGEDAFRAVLC CM |
| Tissue Specificity | Expressed predominantly in thymus and brain. Expression is down-regulated in 28 of 95 tested cancer cell lines. |
| Function | May act as a helicase that plays a role in RNA metabolism in multiple tissues and organs within the developing embryo. |
| Protein Name | Probable Helicase With Zinc Finger DomainDown-Regulated In Human Cancers Protein |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Probable Helicase With Zinc Finger Domain antibodyAnti-Down-Regulated In Human Cancers Protein antibodyAnti-HELZ antibodyAnti-DRHC antibodyAnti-KIAA0054 antibody |
Information sourced from Uniprot.org
