| Host: | Rabbit |
| Applications: | WB/IHC-P/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:50-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | HEBP2 |
| Gene ID: | 23593 |
| Uniprot ID: | HEBP2_HUMAN |
| Immunogen Region: | 1-205 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-205 of human HEBP2 (NP_055135.1). |
| Immunogen Sequence: | MAEPLQPDPGAAEDAAAQAV ETPGWKAPEDAGPQPGSYEI RHYGPAKWVSTSVESMDWDS AIQTGFTKLNSYIQGKNEKE MKIKMTAPVTSYVEPGSGPF SESTITISLYIPSEQQFDPP RPLESDVFIEDRAEMTVFVR SFDGFSSAQKNQEQLLTLAS ILREDGKVFDEKVYYTAGYN SPVKLLNRNNEVWLIQKNEP TKENE |
| Tissue Specificity | Detected in placenta. |
| Function | Can promote mitochondrial permeability transition and facilitate necrotic cell death under different types of stress conditions. |
| Protein Name | Heme-Binding Protein 2Placental Protein 23Pp23Protein Soul |
| Database Links | Reactome: R-HSA-6798695 |
| Cellular Localisation | CytoplasmMitochondrionMainly Localized To The Cytoplasm With A Much Lower Abundance In The Mitochondrion |
| Alternative Antibody Names | Anti-Heme-Binding Protein 2 antibodyAnti-Placental Protein 23 antibodyAnti-Pp23 antibodyAnti-Protein Soul antibodyAnti-HEBP2 antibodyAnti-C6orf34 antibodyAnti-SOUL antibody |
Information sourced from Uniprot.org