| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Hepatoma-derived growth factor-related protein 2 is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
HDGFL2 |
| Gene ID: |
84717 |
| Uniprot ID: |
HDGR2_HUMAN |
| Specificity: |
This antibody detects endogenous levels of HDGF2 at Human, Mouse, Rat |
| Immunogen: |
Synthesized peptide derived from human HDGF2 |
| Function | Acts as an epigenetic regulator of myogenesis in cooperation with DPF3a (isoform 2 of DPF3/BAF45C). Associates with the BAF complex via its interaction with DPF3a and HDGFL2-DPF3a activate myogenic genes by increasing chromatin accessibility through recruitment of SMARCA4/BRG1/BAF190A (ATPase subunit of the BAF complex) to myogenic gene promoters. Promotes the repair of DNA double-strand breaks (DSBs) through the homologous recombination pathway by facilitating the recruitment of the DNA endonuclease RBBP8 to the DSBs. Preferentially binds to chromatin regions marked by H3K9me3, H3K27me3 and H3K36me2. Involved in cellular growth control, through the regulation of cyclin D1 expression. |
| Protein Name | Hepatoma-Derived Growth Factor-Related Protein 2Hdgf-Related Protein 2Hrp-2Hepatoma-Derived Growth Factor 2Hdgf-2 |
| Cellular Localisation | NucleusCytoplasm |
| Alternative Antibody Names | Anti-Hepatoma-Derived Growth Factor-Related Protein 2 antibodyAnti-Hdgf-Related Protein 2 antibodyAnti-Hrp-2 antibodyAnti-Hepatoma-Derived Growth Factor 2 antibodyAnti-Hdgf-2 antibodyAnti-HDGFL2 antibodyAnti-HDGF2 antibodyAnti-HDGFRP2 antibodyAnti-HRP2 antibodyAnti-UNQ785 antibodyAnti-PRO1604 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
