Anti-HDGFL2 antibody (STJA0006918)

SKU:
STJA0006918

Current Stock:
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Hepatoma-derived growth factor-related protein 2 is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: HDGFL2
Gene ID: 84717
Uniprot ID: HDGR2_HUMAN
Specificity: This antibody detects endogenous levels of HDGF2 at Human, Mouse, Rat
Immunogen: Synthesized peptide derived from human HDGF2
Function Acts as an epigenetic regulator of myogenesis in cooperation with DPF3a (isoform 2 of DPF3/BAF45C). Associates with the BAF complex via its interaction with DPF3a and HDGFL2-DPF3a activate myogenic genes by increasing chromatin accessibility through recruitment of SMARCA4/BRG1/BAF190A (ATPase subunit of the BAF complex) to myogenic gene promoters. Promotes the repair of DNA double-strand breaks (DSBs) through the homologous recombination pathway by facilitating the recruitment of the DNA endonuclease RBBP8 to the DSBs. Preferentially binds to chromatin regions marked by H3K9me3, H3K27me3 and H3K36me2. Involved in cellular growth control, through the regulation of cyclin D1 expression.
Protein Name Hepatoma-Derived Growth Factor-Related Protein 2
Hdgf-Related Protein 2
Hrp-2
Hepatoma-Derived Growth Factor 2
Hdgf-2
Cellular Localisation Nucleus
Cytoplasm
Alternative Antibody Names Anti-Hepatoma-Derived Growth Factor-Related Protein 2 antibody
Anti-Hdgf-Related Protein 2 antibody
Anti-Hrp-2 antibody
Anti-Hepatoma-Derived Growth Factor 2 antibody
Anti-Hdgf-2 antibody
Anti-HDGFL2 antibody
Anti-HDGF2 antibody
Anti-HDGFRP2 antibody
Anti-HRP2 antibody
Anti-UNQ785 antibody
Anti-PRO1604 antibody

Information sourced from Uniprot.org

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