Host: | Rabbit |
Applications: | WB |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-HDAC10 is suitable for use in Western Blot research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS + 0.02% NaN3 |
Purification: | Antigen Affinity Purified |
Dilution Range: | WB 1:500-1:1000 IHC ICC IP |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | HDAC10 |
Gene ID: | 83933 |
Uniprot ID: | HDA10_HUMAN |
Specificity: | Reacts with human HDAC10 protein. |
Immunogen: | recombinant human HDAC 10 protein |
Function | Polyamine deacetylase (PDAC), which acts preferentially on N(8)-acetylspermidine, and also on acetylcadaverine and acetylputrescine. Exhibits attenuated catalytic activity toward N(1),N(8)-diacetylspermidine and very low activity, if any, toward N(1)-acetylspermidine. Histone deacetylase activity has been observed in vitro. Has also been shown to be involved in MSH2 deacetylation. The physiological relevance of protein/histone deacetylase activity is unclear and could be very weak. May play a role in the promotion of late stages of autophagy, possibly autophagosome-lysosome fusion and/or lysosomal exocytosis in neuroblastoma cells. May play a role in homologous recombination. May promote DNA mismatch repair. |
Protein Name | Polyamine Deacetylase Hdac10 Histone Deacetylase 10 Hd10 |
Database Links | Reactome: R-HSA-2122947 Reactome: R-HSA-2644606 Reactome: R-HSA-2894862 Reactome: R-HSA-3214815 Reactome: R-HSA-350054 |
Cellular Localisation | Cytoplasm Nucleus Excluded From Nucleoli |
Alternative Antibody Names | Anti-Polyamine Deacetylase Hdac10 antibody Anti-Histone Deacetylase 10 antibody Anti-Hd10 antibody Anti-HDAC10 antibody |
Information sourced from Uniprot.org