| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human/Rat/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (380-460 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000ELISA 1:5000-20000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
HCN1 |
| Gene ID: |
348980 |
| Uniprot ID: |
HCN1_HUMAN |
| Immunogen Region: |
380-460 aa |
| Specificity: |
HCN1 Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: |
Synthesized peptide derived from the human protein at the amino acid range 380-460 |
| Function | Hyperpolarization-activated ion channel that are permeable to sodium and potassium ions. Displays lower selectivity for K(+) over Na(+) ions. Contributes to the native pacemaker currents in heart (If) and in the generation of the I(h) current which controls neuron excitability. Participates in cerebellar mechanisms of motor learning. May mediate responses to sour stimuli. |
| Protein Name | Potassium/Sodium Hyperpolarization-Activated Cyclic Nucleotide-Gated Channel 1Brain Cyclic Nucleotide-Gated Channel 1Bcng-1 |
| Database Links | Reactome: R-HSA-1296061 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Potassium/Sodium Hyperpolarization-Activated Cyclic Nucleotide-Gated Channel 1 antibodyAnti-Brain Cyclic Nucleotide-Gated Channel 1 antibodyAnti-Bcng-1 antibodyAnti-HCN1 antibodyAnti-BCNG1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
