| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
HADH |
| Gene ID: |
3033 |
| Uniprot ID: |
HCDH_HUMAN |
| Specificity: |
This antibody detects endogenous levels of HADH at Human, Mouse, Rat |
| Immunogen: |
Synthesized peptide derived from human HADH |
| Post Translational Modifications | Succinylation at Lys-81, adjacent to a coenzyme A binding site. Desuccinylated by SIRT5. |
| Function | Mitochondrial fatty acid beta-oxidation enzyme that catalyzes the third step of the beta-oxidation cycle for medium and short-chain 3-hydroxy fatty acyl-CoAs (C4 to C10). Plays a role in the control of insulin secretion by inhibiting the activation of glutamate dehydrogenase 1 (GLUD1), an enzyme that has an important role in regulating amino acid-induced insulin secretion. |
| Protein Name | Hydroxyacyl-Coenzyme A Dehydrogenase - MitochondrialHcdhMedium And Short-Chain L-3-Hydroxyacyl-Coenzyme A DehydrogenaseShort-Chain 3-Hydroxyacyl-Coa Dehydrogenase |
| Database Links | Reactome: R-HSA-77310Reactome: R-HSA-77346Reactome: R-HSA-77348Reactome: R-HSA-77350Reactome: R-HSA-77352 |
| Cellular Localisation | Mitochondrion Matrix |
| Alternative Antibody Names | Anti-Hydroxyacyl-Coenzyme A Dehydrogenase - Mitochondrial antibodyAnti-Hcdh antibodyAnti-Medium And Short-Chain L-3-Hydroxyacyl-Coenzyme A Dehydrogenase antibodyAnti-Short-Chain 3-Hydroxyacyl-Coa Dehydrogenase antibodyAnti-HADH antibodyAnti-HAD antibodyAnti-HAD1 antibodyAnti-HADHSC antibodyAnti-SCHAD antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
