Anti-HACL1 antibody (200-300 aa) (STJ11106391)

SKU:
STJ11106391
£112.50 - £524.50
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Gene Symbol: HACL1
Gene ID: 26061
Uniprot ID: HACL1_HUMAN
Immunogen Region: 200-300 aa
Specificity: A synthetic peptide corresponding to a sequence within amino acids 200-300 of human HACL1 (NP_036392.2).
Immunogen Sequence: TSAVCTAASVIRNAKQPLLI IGKGAAYAHAEESIKKLVEQ YKLPFLPTPMGKGVVPDNHP YCVGAARSRALQFADVIVLF GARLNWILHFGLPPRYQPDV K
Tissue Specificity Widely expressed.
Function Peroxisomal 2-OH acyl-CoA lyase involved in the cleavage (C1 removal) reaction in the fatty acid alpha-oxydation in a thiamine pyrophosphate (TPP)-dependent manner. Involved in the degradation of 3-methyl-branched fatty acids like phytanic acid and the shortening of 2-hydroxy long-chain fatty acids. Plays a significant role in the biosynthesis of heptadecanal in the liver.
Protein Name 2-Hydroxyacyl-Coa Lyase 1
2-Hydroxyphytanoyl-Coa Lyase
2-Hpcl
Phytanoyl-Coa 2-Hydroxylase 2
Database Links Reactome: R-HSA-389599
Reactome: R-HSA-9033241
Cellular Localisation Peroxisome
Alternative Antibody Names Anti-2-Hydroxyacyl-Coa Lyase 1 antibody
Anti-2-Hydroxyphytanoyl-Coa Lyase antibody
Anti-2-Hpcl antibody
Anti-Phytanoyl-Coa 2-Hydroxylase 2 antibody
Anti-HACL1 antibody
Anti-HPCL antibody
Anti-HPCL2 antibody
Anti-PHYH2 antibody
Anti-HSPC279 antibody

Information sourced from Uniprot.org

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