| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: |
HACL1 |
| Gene ID: |
26061 |
| Uniprot ID: |
HACL1_HUMAN |
| Immunogen Region: |
200-300 aa |
| Specificity: |
A synthetic peptide corresponding to a sequence within amino acids 200-300 of human HACL1 (NP_036392.2). |
| Immunogen Sequence: |
TSAVCTAASVIRNAKQPLLI IGKGAAYAHAEESIKKLVEQ YKLPFLPTPMGKGVVPDNHP YCVGAARSRALQFADVIVLF GARLNWILHFGLPPRYQPDV K |
| Tissue Specificity | Widely expressed. |
| Function | Peroxisomal 2-OH acyl-CoA lyase involved in the cleavage (C1 removal) reaction in the fatty acid alpha-oxydation in a thiamine pyrophosphate (TPP)-dependent manner. Involved in the degradation of 3-methyl-branched fatty acids like phytanic acid and the shortening of 2-hydroxy long-chain fatty acids. Plays a significant role in the biosynthesis of heptadecanal in the liver. |
| Protein Name | 2-Hydroxyacyl-Coa Lyase 12-Hydroxyphytanoyl-Coa Lyase2-HpclPhytanoyl-Coa 2-Hydroxylase 2 |
| Database Links | Reactome: R-HSA-389599Reactome: R-HSA-9033241 |
| Cellular Localisation | Peroxisome |
| Alternative Antibody Names | Anti-2-Hydroxyacyl-Coa Lyase 1 antibodyAnti-2-Hydroxyphytanoyl-Coa Lyase antibodyAnti-2-Hpcl antibodyAnti-Phytanoyl-Coa 2-Hydroxylase 2 antibodyAnti-HACL1 antibodyAnti-HPCL antibodyAnti-HPCL2 antibodyAnti-PHYH2 antibodyAnti-HSPC279 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
