| Host: | Rabbit |
| Applications: | WB/IHC/IF/ELISA |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Granzyme H (51-100 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000IHC 1:100-1:300IF 1:200-1:1000ELISA 1:40000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | GZMH |
| Gene ID: | 2999 |
| Uniprot ID: | GRAH_HUMAN |
| Immunogen Region: | 51-100 aa |
| Specificity: | Granzyme H Polyclonal Antibody detects endogenous levels of Granzyme H protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human GRAH at the amino acid range 51-100 |
| Function | Cytotoxic chymotrypsin-like serine protease with preference for bulky and aromatic residues at the P1 position and acidic residues at the P3' and P4' sites. Probably necessary for target cell lysis in cell-mediated immune responses. Participates in the antiviral response via direct cleavage of several proteins essential for viral replication. |
| Protein Name | Granzyme HCcp-XCathepsin G-Like 2Ctsgl2Cytotoxic T-Lymphocyte ProteinaseCytotoxic Serine Protease CCsp-C |
| Database Links | Reactome: R-HSA-2022377Reactome: R-HSA-381426 |
| Cellular Localisation | Cytolytic Granule |
| Alternative Antibody Names | Anti-Granzyme H antibodyAnti-Ccp-X antibodyAnti-Cathepsin G-Like 2 antibodyAnti-Ctsgl2 antibodyAnti-Cytotoxic T-Lymphocyte Proteinase antibodyAnti-Cytotoxic Serine Protease C antibodyAnti-Csp-C antibodyAnti-GZMH antibodyAnti-CGL2 antibodyAnti-CTSGL2 antibody |
Information sourced from Uniprot.org