Anti-GYPC antibody (109-128 aa) [R04-8F4] (STJA0010780)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide of human Glycophorin C
General Information
| Short Description | Rabbit monoclonal anti-Glycophorin C (109-128 aa) for use in WB, ICC, IF and IP in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ICC/IF/IP |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R04-8F4 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.3 mg/mL |
| Purification | Affinity Purified |
| Dilution Range | WB 1:500-1:1000IF 1:50-1:200IP 1:20 |
| Formulation | 50mM Tris-Glycine (pH7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | GYPC |
| Gene ID | 2995 |
| Uniprot ID | GLPC_HUMAN |
| Immunogen | A synthetic peptide of human Glycophorin C |
| Immunogen Region | 109-128 aa |
Additional Info
| Tissue Specificity | Glycophorin-C is expressed in erythrocytes. Glycophorin-D and IsoGPC are ubiquitously expressed. |
| Post Translational Modifications | O-glycosylated with core 1 or possibly core 8 glycans. |
| Function | This protein is a minor sialoglycoprotein in human erythrocyte membranes. The blood group Gerbich antigens and receptors for Plasmodium falciparum merozoites are most likely located within the extracellular domain. Glycophorin-C plays an important role in regulating the stability of red cells. |
| Protein Name | Glycophorin-CGlycoconnectinGlycophorin-DGpdGlycoprotein BetaPas-2'Sialoglycoprotein DCd Antigen Cd236 |
| Database Links | Reactome: R-HSA-202733 |
| Cellular Localisation | Cell MembraneSingle-Pass Type Iii Membrane ProteinLinked To The Membrane Via Band 41 |
| Alternative Antibody Names | Anti-Glycophorin-C antibodyAnti-Glycoconnectin antibodyAnti-Glycophorin-D antibodyAnti-Gpd antibodyAnti-Glycoprotein Beta antibodyAnti-Pas-2' antibodyAnti-Sialoglycoprotein D antibodyAnti-Cd Antigen Cd236 antibodyAnti-GYPC antibodyAnti-GLPC antibodyAnti-GPC antibody |
Information sourced from Uniprot.org