| Host: | Goat |
| Applications: | Pep-ELISA/WB/IHC |
| Reactivity: | Human/Mouse/Rat/Dog |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-GULP1/CED6 (C-Term) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:64000.WB: Approx 35kDa band observed in Human Placenta lysates (calculated MW of 34.5kDa according to NP_057399.1). Recommended concentration: 0.2-0.6µg/ml.An additional band of unknown identity |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | GULP1 |
| Gene ID: | 51454 |
| Uniprot ID: | GULP1_HUMAN |
| Immunogen Region: | C-Term |
| Accession Number: | NP_057399.1 |
| Immunogen Sequence: | EGTVFCLDPLDSRC |
| Function | May function as an adapter protein. Required for efficient phagocytosis of apoptotic cells. Modulates cellular glycosphingolipid and cholesterol transport. May play a role in the internalization and endosomal trafficking of various LRP1 ligands, such as PSAP. Increases cellular levels of GTP-bound ARF6. |
| Protein Name | Ptb Domain-Containing Engulfment Adapter Protein 1Cell Death Protein 6 HomologPtb Domain Adapter Protein Ced-6Protein Gulp |
| Cellular Localisation | CytoplasmMay Associate With The Cytoplasmic Side Of The Plasma Membrane And Early Endosomes |
| Alternative Antibody Names | Anti-Ptb Domain-Containing Engulfment Adapter Protein 1 antibodyAnti-Cell Death Protein 6 Homolog antibodyAnti-Ptb Domain Adapter Protein Ced-6 antibodyAnti-Protein Gulp antibodyAnti-GULP1 antibodyAnti-CED6 antibodyAnti-GULP antibody |
Information sourced from Uniprot.org