Anti-GUCY1B3 antibody (1-250) (STJ117471)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal GUCY1B3 (1-250) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:200-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | GUCY1B1 |
| Gene ID | 2983 |
| Uniprot ID | GCYB1_HUMAN |
| Immunogen Region | 1-250 |
| Immunogen Sequence | MYGFVNHALELLVIRNYGPE VWEDIKKEAQLDEEGQFLVR IIYDDSKTYDLVAAASKVLN LNAGEILQMFGKMFFVFCQE SGYDTILRVLGSNVREFLQN LDALHDHLATIYPGMRAPSF RCTDAEKGKGLILHYYSERE GLQDIVIGIIKTVAQQIHGT EIDMKVIQQRNEECDHTQFL IEEKESKEEDFYEDLDRFEE NGTQESRISPYTFCKAFPFH IIFDRDLVVTQCGNAIYRV |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human Guanylyl Cyclase beta 1 (Guanylyl Cyclase beta 1 (GUCY1B3) ) (NP_000848.1). |
Additional Info
| Tissue Specificity | Detected in brain cortex and cerebellum (at protein level). |
| Function | Mediates responses to nitric oxide (NO) by catalyzing the biosynthesis of the signaling molecule cGMP. |
| Protein Name | Guanylate Cyclase Soluble Subunit Beta-1Gcs-Beta-1Guanylate Cyclase Soluble Subunit Beta-3Gcs-Beta-3Soluble Guanylate Cyclase Small Subunit |
| Database Links | Reactome: R-HSA-392154Reactome: R-HSA-445355 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Guanylate Cyclase Soluble Subunit Beta-1 antibodyAnti-Gcs-Beta-1 antibodyAnti-Guanylate Cyclase Soluble Subunit Beta-3 antibodyAnti-Gcs-Beta-3 antibodyAnti-Soluble Guanylate Cyclase Small Subunit antibodyAnti-GUCY1B1 antibodyAnti-GUC1B3 antibodyAnti-GUCSB3 antibodyAnti-GUCY1B3 antibody |
Information sourced from Uniprot.org