| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | GTF3A |
| Gene ID: | 2971 |
| Uniprot ID: | TF3A_HUMAN |
| Immunogen Region: | 1-100 |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human GTF3A (NP_002088.2). |
| Immunogen Sequence: | MDPPAVVAESVSSLTIADAF IAAGESSAPTPPRPALPRRF ICSFPDCSANYSKAWKLDAH LCKHTGERPFVCDYEGCGKA FIRDYHLSRHILTHTGEKPF |
| Tissue Specificity | Ubiquitous. |
| Function | Involved in ribosomal large subunit biogenesis. Binds the approximately 50 base pairs internal control region (ICR) of 5S ribosomal RNA genes. It is required for their RNA polymerase III-dependent transcription and may also maintain the transcription of other genes. Also binds the transcribed 5S RNA's. |
| Protein Name | Transcription Factor IiiaTfiiia |
| Database Links | Reactome: R-HSA-749476Reactome: R-HSA-76061 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Transcription Factor Iiia antibodyAnti-Tfiiia antibodyAnti-GTF3A antibody |
Information sourced from Uniprot.org