Anti-GTF2IRD1 antibody (Internal) (STJ70971)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-GTF2IRD1 (Internal) is suitable for use in ELISA, Western Blot, Immunofluorescence and Flow Cytometry research applications. |
| Applications | Pep-ELISA/WB/IF/FC |
| Host | Goat |
| Reactivity | Human/Mouse/Rat/Dog |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:64000.WB: Approx 110kDa band observed in nuclear lysates of cell line Jurkat (calculated MW of 106kDa according to NP_057412.1). Recommended concentration: 0.5-1µg/ml. Primary incubation 1 hour |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | GTF2IRD1 |
| Gene ID | 9569 |
| Uniprot ID | GT2D1_HUMAN |
| Accession Number | NP_057412.1; NP_005676.3; NP_001186136.1 |
| Immunogen Region | Internal |
| Immunogen Sequence | NKFTKDTTKLEPAS |
Additional Info
| Function | May be a transcription regulator involved in cell-cycle progression and skeletal muscle differentiation. May repress GTF2I transcriptional functions, by preventing its nuclear residency, or by inhibiting its transcriptional activation. May contribute to slow-twitch fiber type specificity during myogenesis and in regenerating muscles. Binds troponin I slow-muscle fiber enhancer (USE B1). Binds specifically and with high affinity to the EFG sequences derived from the early enhancer of HOXC8. |
| Protein Name | General Transcription Factor Ii-I Repeat Domain-Containing Protein 1Gtf2i Repeat Domain-Containing Protein 1General Transcription Factor IiiMustrd1/BenMuscle Tfii-I Repeat Domain-Containing Protein 1Slow-Muscle-Fiber Enhancer-Binding ProteinUse B1-Binding ProteinWilliams-Beuren Syndrome Chromosomal Region 11 ProteinWilliams-Beuren Syndrome Chromosomal Region 12 Protein |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-General Transcription Factor Ii-I Repeat Domain-Containing Protein 1 antibodyAnti-Gtf2i Repeat Domain-Containing Protein 1 antibodyAnti-General Transcription Factor Iii antibodyAnti-Mustrd1/Ben antibodyAnti-Muscle Tfii-I Repeat Domain-Containing Protein 1 antibodyAnti-Slow-Muscle-Fiber Enhancer-Binding Protein antibodyAnti-Use B1-Binding Protein antibodyAnti-Williams-Beuren Syndrome Chromosomal Region 11 Protein antibodyAnti-Williams-Beuren Syndrome Chromosomal Region 12 Protein antibodyAnti-GTF2IRD1 antibodyAnti-CREAM1 antibodyAnti-GTF3 antibodyAnti-MUSTRD1 antibodyAnti-RBAP2 antibodyAnti-WBSCR11 antibodyAnti-WBSCR12 antibody |
Information sourced from Uniprot.org