• Western blot analysis of lysates from U2OS cells, primary antibody was diluted at 1:1000, 4°C over night

Anti-GTDC1 antibody (273-323 aa) (STJ195917)

SKU:
STJ195917

Current Stock:
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Glycosyltransferase-like domain-containing protein 1 (273-323 aa) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: GTDC1
Gene ID: 79712
Uniprot ID: QTMAN_HUMAN
Immunogen Region: 273-323 aa
Specificity: This antibody detects endogenous levels of GTDC1 at Human/Mouse/Rat
Immunogen: Synthesized peptide derived from the human GTDC1 at the amino acid range 273-323
Function Glycosyltransferase that specifically catalyzes mannosylation of cytoplasmic tRNA(Asp) modified with queuosine at position 34 (queuosine(34)). Mannosylates the cyclopentene moiety of queuosine(34) in tRNA(Asp) to form mannosyl-queuosine(34). Mannosylation of queuosine(34) in tRNA(Asp) is required to slow-down elongation at cognate codons, GAC and GAU, thereby regulating protein translation.
Protein Name Trna-Queuosine Alpha-Mannosyltransferase
Qtman
Glycosyltransferase-Like Domain-Containing Protein 1
Mannosyltransferase-Like Protein Xa
Mat-Xa
Cellular Localisation Cytoplasm
Nucleus
Alternative Antibody Names Anti-Trna-Queuosine Alpha-Mannosyltransferase antibody
Anti-Qtman antibody
Anti-Glycosyltransferase-Like Domain-Containing Protein 1 antibody
Anti-Mannosyltransferase-Like Protein Xa antibody
Anti-Mat-Xa antibody
Anti-GTDC1 antibody
Anti-QTMAN antibody

Information sourced from Uniprot.org

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