| Host: | Goat |
| Applications: | Pep-ELISA/WB/IHC |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-GSTM4 (Internal) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:128000.WB: Approx 26kDa band observed in lysates of cell line HeLa and in Rat Lung lysates (calculated MW of 25.6kDa according to Human NP_000841.1 and Rat NP_001019475.1 ). Recommended concentr |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | GSTM4 |
| Gene ID: | 2948 |
| Uniprot ID: | GSTM4_HUMAN |
| Immunogen Region: | Internal |
| Accession Number: | NP_000841.1; NP_671489.1 |
| Specificity: | This antibody is expected to recognize both reported isoforms (NP_000841.1; NP_671489.1). |
| Immunogen Sequence: | DVSNQLARVCYSPD |
| Function | Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Catalyzes the conjugation of leukotriene A4 with reduced glutathione (GSH) to form leukotriene C4. Can also catalyze the transfer of a glutathionyl group from glutathione (GSH) to 13(S),14(S)-epoxy-docosahexaenoic acid to form maresin conjugate in tissue regeneration 1 (MCTR1), a bioactive lipid mediator that possess potent anti-inflammatory and proresolving actions. |
| Protein Name | Glutathione S-Transferase Mu 4Gst Class-Mu 4Gst-Mu2Gstm4-4Leukotriene C4 Synthase Gstm4 |
| Database Links | Reactome: R-HSA-156590Reactome: R-HSA-9026762 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Glutathione S-Transferase Mu 4 antibodyAnti-Gst Class-Mu 4 antibodyAnti-Gst-Mu2 antibodyAnti-Gstm4-4 antibodyAnti-Leukotriene C4 Synthase Gstm4 antibodyAnti-GSTM4 antibody |
Information sourced from Uniprot.org