| Short Description : | Rabbit polyclonal anti-Metabotropic glutamate receptor 7 (866-915 aa) for use in WB, IHC, IF and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IHC/IF/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-1:2000IHC 1:100-1:300IF 1:200-1:1000ELISA 1:20000 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | GRM7 |
| Gene ID: | 2917 |
| Uniprot ID: | GRM7_HUMAN |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human mGluR7 at the amino acid range 866-915 |
| Immunogen Region: | 866-915 aa |
| Specificity: | mGluR-7 Polyclonal Antibody detects endogenous levels of mGluR-7 protein. |
| Post Translational Modifications | N-glycosylated. |
| Function | G-protein coupled receptor activated by glutamate that regulates axon outgrowth through the MAPK-cAMP-PKA signaling pathway during neuronal development. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors, such as adenylate cyclase that it inhibits. |
| Protein Name | Metabotropic Glutamate Receptor 7Mglur7 |
| Database Links | Reactome: R-HSA-418594Reactome: R-HSA-420499 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Metabotropic Glutamate Receptor 7 antibodyAnti-Mglur7 antibodyAnti-GRM7 antibodyAnti-GPRC1G antibodyAnti-MGLUR7 antibody |
Information sourced from Uniprot.org
