Anti-GRM2 nanobody [SAA1127] (STJN000270)

SKU:
STJN000270
$510.98 - $2,203.88
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Host: Alpaca
Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Alpaca monoclonal nanobody anti-Metabotropic Glutamate Receptor 2 is suitable for use in ELISA research applications.
Clonality : Monoclonal
Clone ID : SAA1127
Conjugation: Unconjugated
Isotype: VHH-8His-Cys-tag
Formulation: 0.01M PBS, pH 7.4.
Purification: Purified by Nickel column.
Concentration: 1 mg/mL
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at-20°C 12 months. Store at-80°C long term.
Gene Symbol: GRM2
Gene ID: 2912
Uniprot ID: GRM2_HUMAN
Function G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. May mediate suppression of neurotransmission or may be involved in synaptogenesis or synaptic stabilization.
Protein Name Metabotropic Glutamate Receptor 2
Mglur2
Database Links Reactome: R-HSA-418594
Reactome: R-HSA-420499
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Synapse
Cell Projection
Dendrite
Alternative Nanobody Names Anti-Metabotropic Glutamate Receptor 2 nanobody
Anti-Mglur2 nanobody
Anti-GRM2 nanobody
Anti-GPRC1B nanobody
Anti-MGLUR2 nanobody

Information sourced from Uniprot.org