| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | GRHPR |
| Gene ID: | 9380 |
| Uniprot ID: | GRHPR_HUMAN |
| Immunogen Region: | 100-328 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 100-328 of human GRHPR (NP_036335.1). |
| Immunogen Sequence: | VGYTPDVLTDTTAELAVSLL LTTCRRLPEAIEEVKNGGWT SWKPLWLCGYGLTQSTVGII GLGRIGQAIARRLKPFGVQR FLYTGRQPRPEEAAEFQAEF VSTPELAAQSDFIVVACSLT PATEGLCNKDFFQKMKETAV FINISRGDVVNQDDLYQALA SGKIAAAGLDVTSPEPLPTN HPLLTLKNCVILPHIGSATH RTRNTMSLLAANNLLAGLRG EPMPSELKL |
| Tissue Specificity | Ubiquitous. Most abundantly expressed in the liver. |
| Function | Enzyme with hydroxy-pyruvate reductase, glyoxylate reductase and D-glycerate dehydrogenase enzymatic activities. Reduces hydroxypyruvate to D-glycerate, glyoxylate to glycolate, oxidizes D-glycerate to hydroxypyruvate. |
| Protein Name | Glyoxylate Reductase/Hydroxypyruvate Reductase |
| Database Links | Reactome: R-HSA-389661 |
| Alternative Antibody Names | Anti-Glyoxylate Reductase/Hydroxypyruvate Reductase antibodyAnti-GRHPR antibodyAnti-GLXR antibodyAnti-MSTP035 antibody |
Information sourced from Uniprot.org