| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:200-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | GPT |
| Gene ID: | 2875 |
| Uniprot ID: | ALAT1_HUMAN |
| Immunogen Region: | 1-190 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human GPT (NP_005300.1). |
| Immunogen Sequence: | MASSTGDRSQAVRHGLRAKV LTLDGMNPRVRRVEYAVRGP IVQRALELEQELRQGVKKPF TEVIRANIGDAQAMGQRPIT FLRQVLALCVNPDLLSSPNF PDDAKKRAERILQACGGHSL GAYSVSSGIQLIREDVARYI ERRDGGIPADPNNVFLSTGA SDAIVTVLKLLVAGEGHTRT GVLIPIPQYP |
| Tissue Specificity | Liver, kidney, heart, and skeletal muscles. Expressed at moderate levels in the adipose tissue. |
| Function | Catalyzes the reversible transamination between alanine and 2-oxoglutarate to form pyruvate and glutamate. Participates in cellular nitrogen metabolism and also in liver gluconeogenesis starting with precursors transported from skeletal muscles. |
| Protein Name | Alanine Aminotransferase 1Alt1Glutamate Pyruvate Transaminase 1Gpt 1Glutamic--Alanine Transaminase 1Glutamic--Pyruvic Transaminase 1 |
| Database Links | Reactome: R-HSA-70268Reactome: R-HSA-8964540 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Alanine Aminotransferase 1 antibodyAnti-Alt1 antibodyAnti-Glutamate Pyruvate Transaminase 1 antibodyAnti-Gpt 1 antibodyAnti-Glutamic--Alanine Transaminase 1 antibodyAnti-Glutamic--Pyruvic Transaminase 1 antibodyAnti-GPT antibodyAnti-AAT1 antibodyAnti-GPT1 antibody |
Information sourced from Uniprot.org