• Western blot analysis of the lysates from HeLa cells using GPRC6A antibody.
  • Western blot analysis of lysates from Jurkat cells, using GPRC6A Antibody. The lane on the right is blocked with the synthesized peptide.
  • Western blot analysis of various cells using Antibody diluted at 1:1000. Secondary antibody was diluted at 1:20000
  • Immunofluorescence analysis of MCF7 cells, using GPRC6A Antibody. The picture on the right is blocked with the synthesized peptide.
  • Western blot analysis of Jurkat cells using GPRC6A Polyclonal Antibody diluted at 1：1000

Anti-GPRC6A antibody (471-520 aa) (STJ93405)

SKU:
STJ93405

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IF/ELISA
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-G-protein coupled receptor family C group 6 member A (471-520 aa) is suitable for use in Western Blot, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IF 1:200-1:1000
ELISA 1:5000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: GPRC6A
Gene ID: 222545
Uniprot ID: GPC6A_HUMAN
Immunogen Region: 471-520 aa
Specificity: GPRC6A Polyclonal Antibody detects endogenous levels of GPRC6A protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human GPRC6A at the amino acid range 471-520
Function Receptor activated by multiple ligands, including osteocalcin (BGLAP), basic amino acids, and various cations. Activated by amino acids with a preference for basic amino acids such as L-Lys, L-Arg and L-ornithine but also by small and polar amino acids. The L-alpha amino acids respond is augmented by divalent cations Ca(2+) and Mg(2+). Seems to act through a G(q)/G(11) and G(i)-coupled pathway. Regulates testosterone production by acting as a ligand for uncarboxylated osteocalcin hormone: osteocalcin-binding at the surface of Leydig cells initiates a signaling response that promotes the expression of enzymes required for testosterone synthesis in a CREB-dependent manner. Mediates the non-genomic effects of androgens in multiple tissue. May coordinate nutritional and hormonal anabolic signals through the sensing of extracellular amino acids, osteocalcin, divalent ions and its responsiveness to anabolic steroids.
Protein Name G-Protein Coupled Receptor Family C Group 6 Member A
Hgprc6a
G-Protein Coupled Receptor Gpcr33
Hgpcr33
Database Links Reactome: R-HSA-416476
Reactome: R-HSA-420499
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-G-Protein Coupled Receptor Family C Group 6 Member A antibody
Anti-Hgprc6a antibody
Anti-G-Protein Coupled Receptor Gpcr33 antibody
Anti-Hgpcr33 antibody
Anti-GPRC6A antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance