| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | S4128RM |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | GPRC5B |
| Gene ID: | 51704 |
| Uniprot ID: | GPC5B_HUMAN |
| Immunogen Region: | 304-403 |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 304-403 of human GPRC5B (NP_057319.1). |
| Immunogen Sequence: | TPNYFDTSQPRMRETAFEED VQLPRAYMENKAFSMDEHNA ALRTAGFPNGSLGKRPSGSL GKRPSAPFRSNVYQPTEMAV VLNGGTIPTAPPSHTGRHLW |
| Tissue Specificity | Expression is high in kidney, pancreas, and testis, medium in brain, heart, prostate, small intestine, and spleen, low in liver, placenta, skeletal muscle, colon, ovary, and thymus, and not detectable in lung and peripheral leukocyte. highly expressed in most brain areas examined, with the highest levels observed in corpus callosum, caudate nucleus, putamen, substantia nigra, thalamus, hippocampus, and spinal cord as well as in dorsal root ganglia (DRG). Expressed in glia limitans, ependymal cells, astrocyte cell bodies, the perivascular region in astrocyte endfeet, but not in neurons. In the periphery, expression levels are relatively low, compared to the CNS, with the strongest expression detected in pancreas, testis, uterus, and stomach. |
| Function | G-protein coupled receptor involved in the regulation of cell volume. |
| Protein Name | G-Protein Coupled Receptor Family C Group 5 Member BA-69g12.1Retinoic Acid-Induced Gene 2 ProteinRaig-2 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinCytoplasmic Vesicle MembraneLocalized In The Plasma Membrane And Perinuclear Vesicles |
| Alternative Antibody Names | Anti-G-Protein Coupled Receptor Family C Group 5 Member B antibodyAnti-A-69g12.1 antibodyAnti-Retinoic Acid-Induced Gene 2 Protein antibodyAnti-Raig-2 antibodyAnti-GPRC5B antibodyAnti-RAIG2 antibody |
Information sourced from Uniprot.org