| Host: | Rabbit |
| Applications: | WB/IF/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Ovarian cancer G-protein coupled receptor 1 (281-330 aa) is suitable for use in Western Blot, Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000IF 1:200-1:1000ELISA 1:5000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | GPR68 |
| Gene ID: | 8111 |
| Uniprot ID: | OGR1_HUMAN |
| Immunogen Region: | 281-330 aa |
| Specificity: | GPR68 Polyclonal Antibody detects endogenous levels of GPR68 protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human SPR1 at the amino acid range 281-330 |
| Function | Proton-sensing receptor involved in pH homeostasis. May represents an osteoblastic pH sensor regulating cell-mediated responses to acidosis in bone. Mediates its action by association with G proteins that stimulates inositol phosphate (IP) production or Ca(2+) mobilization. The receptor is almost silent at pH 7.8 but fully activated at pH 6.8. Also functions as a metastasis suppressor gene in prostate cancer. |
| Protein Name | Ovarian Cancer G-Protein Coupled Receptor 1Ogr-1G-Protein Coupled Receptor 68Gpr12aSphingosylphosphorylcholine Receptor |
| Database Links | Reactome: R-HSA-373076Reactome: R-HSA-416476 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Ovarian Cancer G-Protein Coupled Receptor 1 antibodyAnti-Ogr-1 antibodyAnti-G-Protein Coupled Receptor 68 antibodyAnti-Gpr12a antibodyAnti-Sphingosylphosphorylcholine Receptor antibodyAnti-GPR68 antibodyAnti-OGR1 antibody |
Information sourced from Uniprot.org