Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-GPR17 (1-94) is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:1000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
GPR17 |
Gene ID: |
2840 |
Uniprot ID: |
GPR17_HUMAN |
Immunogen Region: |
1-94 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-94 of human GPR17 (NP_005282.1). |
Immunogen Sequence: |
MSKRSWWAGSRKPPREMLKL SGSDSSQSMNGLEVAPPGLI TNFSLATAEQCGQETPLENM LFASFYLLDFILALVGNTLA LWLFIRDHKSGTPA |
Tissue Specificity | Expressed in brain, kidney, heart and umbilical vein endothelial cells. Highest level in brain. |
Function | Dual specificity receptor for uracil nucleotides and cysteinyl leukotrienes (CysLTs). Signals through G(i) and inhibition of adenylyl cyclase. May mediate brain damage by nucleotides and CysLTs following ischemia. |
Protein Name | Uracil Nucleotide/Cysteinyl Leukotriene ReceptorUdp/Cyslt ReceptorG-Protein Coupled Receptor 17P2y-Like ReceptorR12 |
Database Links | Reactome: R-HSA-391906Reactome: R-HSA-416476Reactome: R-HSA-417957Reactome: R-HSA-418594 |
Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
Alternative Antibody Names | Anti-Uracil Nucleotide/Cysteinyl Leukotriene Receptor antibodyAnti-Udp/Cyslt Receptor antibodyAnti-G-Protein Coupled Receptor 17 antibodyAnti-P2y-Like Receptor antibodyAnti-R12 antibodyAnti-GPR17 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance