| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | GPR17 |
| Gene ID: | 2840 |
| Uniprot ID: | GPR17_HUMAN |
| Immunogen Region: | 1-94 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-94 of human GPR17 (NP_005282.1). |
| Immunogen Sequence: | MSKRSWWAGSRKPPREMLKL SGSDSSQSMNGLEVAPPGLI TNFSLATAEQCGQETPLENM LFASFYLLDFILALVGNTLA LWLFIRDHKSGTPA |
| Tissue Specificity | Expressed in brain, kidney, heart and umbilical vein endothelial cells. Highest level in brain. |
| Function | Dual specificity receptor for uracil nucleotides and cysteinyl leukotrienes (CysLTs). Signals through G(i) and inhibition of adenylyl cyclase. May mediate brain damage by nucleotides and CysLTs following ischemia. |
| Protein Name | Uracil Nucleotide/Cysteinyl Leukotriene ReceptorUdp/Cyslt ReceptorG-Protein Coupled Receptor 17P2y-Like ReceptorR12 |
| Database Links | Reactome: R-HSA-391906Reactome: R-HSA-416476Reactome: R-HSA-417957Reactome: R-HSA-418594 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Uracil Nucleotide/Cysteinyl Leukotriene Receptor antibodyAnti-Udp/Cyslt Receptor antibodyAnti-G-Protein Coupled Receptor 17 antibodyAnti-P2y-Like Receptor antibodyAnti-R12 antibodyAnti-GPR17 antibody |
Information sourced from Uniprot.org
