Host: |
Rabbit |
Applications: |
IHC/IF |
Reactivity: |
Human/Rat/Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Protein GPR15LG (19-69 aa) is suitable for use in Immunohistochemistry and Immunofluorescence research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
IHC-P 1:50-200IF 1:50-200 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
GPR15LG |
Gene ID: |
387695 |
Uniprot ID: |
GP15L_HUMAN |
Immunogen Region: |
19-69 aa |
Specificity: |
This antibody detects endogenous levels of CJ099 at Human |
Immunogen: |
Synthesized peptide derived from the human CJ099 at the amino acid range 19-69 |
Function | Highly cationic protein that has multiple functions. Acts as a chemotactic factor that mediates lymphocytes recruitment to epithelia through binding and activation of the G-protein coupled receptor GPR15. May be a tumor suppressor.together with SUSD2 has a growth inhibitory effect on colon cancer cells which includes G1 cell cycle arrest. May regulate keratinocyte proliferation. In addition, through activation of Mas-related G protein-coupled receptors (MRGPRs) contributes to pruritogenesis by activating itch-selective sensory neurons and mast cells degranulation. Has antimicrobial activity against Gram-positive bacteria, including Staphylococcus aureus and Actinomyces spec., and Mycoplasma hominis and lentivirus. |
Protein Name | Protein Gpr15lgAntimicrobial Peptide With 57 Amino Acid ResiduesAp-57Antimicrobial Peptide-57Colon-Derived Susd2 Binding FactorCsbfProtein Gpr15 LigandProtein Gpr15lSecreted Protein C10orf99 |
Cellular Localisation | Secreted |
Alternative Antibody Names | Anti-Protein Gpr15lg antibodyAnti-Antimicrobial Peptide With 57 Amino Acid Residues antibodyAnti-Ap-57 antibodyAnti-Antimicrobial Peptide-57 antibodyAnti-Colon-Derived Susd2 Binding Factor antibodyAnti-Csbf antibodyAnti-Protein Gpr15 Ligand antibodyAnti-Protein Gpr15l antibodyAnti-Secreted Protein C10orf99 antibodyAnti-GPR15LG antibodyAnti-C10orf99 antibodyAnti-GPR15L antibodyAnti-UNQ1833 antibodyAnti-PRO3446 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance