• Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Antibody was diluted at 1:200 (4°C overnight). 2, Tris-EDTA, pH9.0 was used for antigen retrieval. 3, Secondary antibody was diluted at 1:200 (room temperature, 30min).

Anti-GPR15LG antibody (19-69 aa) (STJ196197)

SKU:
STJ196197

$62.10 - $305.10
Current Stock:
Host: Rabbit
Applications: IHC/IF
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Protein GPR15LG (19-69 aa) is suitable for use in Immunohistochemistry and Immunofluorescence research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: IHC-P 1:50-200
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: GPR15LG
Gene ID: 387695
Uniprot ID: GP15L_HUMAN
Immunogen Region: 19-69 aa
Specificity: This antibody detects endogenous levels of CJ099 at Human
Immunogen: Synthesized peptide derived from the human CJ099 at the amino acid range 19-69
Function Highly cationic protein that has multiple functions. Acts as a chemotactic factor that mediates lymphocytes recruitment to epithelia through binding and activation of the G-protein coupled receptor GPR15. May be a tumor suppressor.together with SUSD2 has a growth inhibitory effect on colon cancer cells which includes G1 cell cycle arrest. May regulate keratinocyte proliferation. In addition, through activation of Mas-related G protein-coupled receptors (MRGPRs) contributes to pruritogenesis by activating itch-selective sensory neurons and mast cells degranulation. Has antimicrobial activity against Gram-positive bacteria, including Staphylococcus aureus and Actinomyces spec., and Mycoplasma hominis and lentivirus.
Protein Name Protein Gpr15lg
Antimicrobial Peptide With 57 Amino Acid Residues
Ap-57
Antimicrobial Peptide-57
Colon-Derived Susd2 Binding Factor
Csbf
Protein Gpr15 Ligand
Protein Gpr15l
Secreted Protein C10orf99
Cellular Localisation Secreted
Alternative Antibody Names Anti-Protein Gpr15lg antibody
Anti-Antimicrobial Peptide With 57 Amino Acid Residues antibody
Anti-Ap-57 antibody
Anti-Antimicrobial Peptide-57 antibody
Anti-Colon-Derived Susd2 Binding Factor antibody
Anti-Csbf antibody
Anti-Protein Gpr15 Ligand antibody
Anti-Protein Gpr15l antibody
Anti-Secreted Protein C10orf99 antibody
Anti-GPR15LG antibody
Anti-C10orf99 antibody
Anti-GPR15L antibody
Anti-UNQ1833 antibody
Anti-PRO3446 antibody

Information sourced from Uniprot.org

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