| Short Description : | Rabbit polyclonal GPAM (594-828) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | GPAM |
| Gene ID: | 57678 |
| Uniprot ID: | GPAT1_HUMAN |
| Immunogen Region: | 594-828 |
| Immunogen Sequence: | LNKRGLGGPTSTPPNLISQE QLVRKAASLCYLLSNEGTIS LPCQTFYQVCHETVGKFIQY GILTVAEHDDQEDISPSLAE QQWDKKLPEPLSWRSDEEDE DSDFGEEQRDCYLKVSQSKE HQQFITFLQRLLGPLLEAYS SAAIFVHNFSGPVPEPEYLQ KLHKYLITRTERNVAVYAES ATYCLVKNAVKMFKDIGVFK ETKQKRVSVLELSSTFLPQC NRQKLLEYILSFVVL |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 594-828 of human GPAM (NP_001231878.1). |
| Function | Mitochondrial membrane protein that catalyzes the essential first step of biosynthesis of glycerolipids such as triglycerides, phosphatidic acids and lysophosphatidic acids. Esterifies acyl-group from acyl-coenzyme A (acyl-CoA) to the sn-1 position of glycerol-3-phosphate, to produce lysophosphatidic acid. Has a narrow hydrophobic binding cleft that selects for a linear acyl chain. Catalytic activity is higher for substrates with a 16-carbon acyl chain. |
| Protein Name | Glycerol-3-Phosphate Acyltransferase 1 - MitochondrialGpat-1 |
| Database Links | Reactome: R-HSA-1483166Reactome: R-HSA-2426168Reactome: R-HSA-75109Reactome: R-HSA-8931987Reactome: R-HSA-9018519Reactome: R-HSA-9841922 |
| Cellular Localisation | Mitochondrion Outer MembranePeripheral Membrane ProteinAssociated With The Mitochondrion Outer Membrane Of Hepatic Cells Via A Patch Of Basic Residues |
| Alternative Antibody Names | Anti-Glycerol-3-Phosphate Acyltransferase 1 - Mitochondrial antibodyAnti-Gpat-1 antibodyAnti-GPAM antibodyAnti-GPAT1 antibodyAnti-KIAA1560 antibody |
Information sourced from Uniprot.org
