Anti-GP6/GPVI antibody [SRM13370] (STJ11108100)

SKU:
STJ11108100
$0.00
Processing The item has been added
Enquire For Bulk Order

Covered by St John's Laboratory Guarantee

Host: Rabbit
Applications: FC/ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Monoclonal
Clone ID : SRM13370
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS containing 50% Glycerol and 0.05% BSA, preserved with proclin300 or Sodium Azide (as specified on the Certificate of Analysis) , pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: FC, 1:500-1:1000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: GP6
Gene ID: 51206
Uniprot ID: GPVI_HUMAN
Immunogen: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Immunogen Sequence: Human
Post Translational Modifications N-linked glycosylation at Asn-92 is not required for the cell surface expression, but contributes to maximal adhesion to type I collagen, collagen-related peptide (CRP), and, to a lesser extent, to the snake venom C-type lectin convulxin (CVX).
Function Collagen receptor involved in collagen-induced platelet adhesion and activation. Plays a key role in platelet procoagulant activity and subsequent thrombin and fibrin formation. This procoagulant function may contribute to arterial and venous thrombus formation. The signaling pathway involves the FcR gamma-chain, the Src kinases (likely FYN or LYN) and SYK, the adapter protein LAT and leads to the activation of PLCG2.
Protein Name Platelet Glycoprotein Vi
Gpvi
Glycoprotein 6
Database Links Reactome: R-HSA-114604
Reactome: R-HSA-202733
Reactome: R-HSA-75892
Cellular Localisation Isoform 1: Cell Membrane
Single-Pass Membrane Protein
Isoform 2: Cell Membrane
Alternative Antibody Names Anti-Platelet Glycoprotein Vi antibody
Anti-Gpvi antibody
Anti-Glycoprotein 6 antibody
Anti-GP6 antibody

Information sourced from Uniprot.org

Related Products

Model Name Host Clonality Reactivity Application
STJ11105391 Anti-GPVI/GP6 antibody (24-265) (STJ11105391) Rabbit Polyclonal Human WB/ELISA
STJN000301 Anti-GP6/GPVI nanobody [SAA1026] (STJN000301) Alpaca Monoclonal Human ELISA
STJ11108593 Anti-GP6/GPVI antibody {ABflo® 647} (STJ11108593) Rabbit Monoclonal Human FC
STJ11108594 Anti-GP6/GPVI antibody {ABflo® 594} (STJ11108594) Rabbit Monoclonal Human FC
STJA0027026 Anti-GP6 antibody [SAA0163] (STJA0027026) Human Monoclonal Human FC

Related Products

!