Anti-GNL2 antibody (670-750 aa) (STJ191110)

SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human protein at the amino acid range 670-750
STJ191110
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General Information

Short DescriptionRabbit polyclonal anti-Nucleolar GTP-binding protein 2 (670-750 aa) for use in WB and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsWB/ELISA
HostRabbit
ReactivityHuman/Mouse
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityPolyclonal
IsotypeIgG
ConjugationUnconjugated
Concentration1 mg/mL
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution RangeWB 1:500-2000
ELISA 1:5000-20000
FormulationLiquid in PBS containing 50% Glycerol and 0.02% Sodium Azide.
Storage InstructionStore at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolGNL2
Gene ID29889
Uniprot IDNOG2_HUMAN
ImmunogenSynthesized peptide derived from the human protein at the amino acid range 670-750
Immunogen Region670-750 aa
SpecificityNOG2 Polyclonal Antibody detects endogenous levels of protein.

Additional Info

Function GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. May promote cell proliferation possibly by increasing p53/TP53 protein levels, and consequently those of its downstream product CDKN1A/p21, and decreasing RPL23A protein levels.
Protein Name Nucleolar Gtp-Binding Protein 2
Autoantigen Ngp-1
Database Links
Cellular Localisation Nucleus
Nucleolus
Alternative Antibody Names Anti-Nucleolar Gtp-Binding Protein 2 antibody
Anti-Autoantigen Ngp-1 antibody
Anti-GNL2 antibody
Anti-NGP1 antibody

Information sourced from Uniprot.org

Citations

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