| Short Description : | Rabbit polyclonal GNB1L (1-327) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | GNB1L |
| Gene ID: | 54584 |
| Uniprot ID: | GNB1L_HUMAN |
| Immunogen Region: | 1-327 |
| Immunogen Sequence: | MTAPCPPPPPDPQFVLRGTQ SPVHALHFCEGAQAQGRPLL FSGSQSGLVHIWSLQTRRAV TTLDGHGGQCVTWLQTLPQG RQLLSQGRDLKLCLWDLAEG RSAVVDSVCLESVGFCRSSI LAGGQPRWTLAVPGRGSDEV QILEMPSKTSVCALKPKADA KLGMPMCLRLWQADCSSRPL LLAGYEDGSVVLWDVSEQKV CSRIACHEEPVMDLDFDSQK ARGISGSAGKALAVWSLDW |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-327 of human GNB1L (NP_443730.1). |
| Tissue Specificity | Ubiquitous. Highly expressed in heart, liver, skeletal muscle, kidney, spleen, thymus and pancreas. Detected at low levels in lung, placenta and brain. |
| Function | Acts as a critical regulator of DNA damage response (DDR) signaling via specifically regulating phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. |
| Protein Name | Guanine Nucleotide-Binding Protein Subunit Beta-Like Protein 1G Protein Subunit Beta-Like Protein 1Dgcrk3Wd Repeat-Containing Protein 14Wd40 Repeat-Containing Protein Deleted In VcfsWdvcf |
| Database Links | |
| Cellular Localisation | CytoplasmNucleusLocalizes Mainly In Cytosol And To A Lesser Extent In The Nucleus |
| Alternative Antibody Names | Anti-Guanine Nucleotide-Binding Protein Subunit Beta-Like Protein 1 antibodyAnti-G Protein Subunit Beta-Like Protein 1 antibodyAnti-Dgcrk3 antibodyAnti-Wd Repeat-Containing Protein 14 antibodyAnti-Wd40 Repeat-Containing Protein Deleted In Vcfs antibodyAnti-Wdvcf antibodyAnti-GNB1L antibodyAnti-GY2 antibodyAnti-KIAA1645 antibodyAnti-WDR14 antibodyAnti-FKSG1 antibody |
Information sourced from Uniprot.org
