Anti-GM2A antibody (STJA0007727)

SKU:
STJA0007727
£48.00 - £252.00
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-Ganglioside GM2 activator is suitable for use in Western Blot research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: GM2A
Gene ID: 2760
Uniprot ID: SAP3_HUMAN
Specificity: This antibody detects endogenous levels of GM2A at Human, Mouse
Immunogen: Synthesized peptide derived from human GM2A
Function The large binding pocket can accommodate several single chain phospholipids and fatty acids, GM2A also exhibits some calcium-independent phospholipase activity. Binds gangliosides and stimulates ganglioside GM2 degradation. It stimulates only the breakdown of ganglioside GM2 and glycolipid GA2 by beta-hexosaminidase A. It extracts single GM2 molecules from membranes and presents them in soluble form to beta-hexosaminidase A for cleavage of N-acetyl-D-galactosamine and conversion to GM3. Has cholesterol transfer activity.
Protein Name Ganglioside Gm2 Activator
Cerebroside Sulfate Activator Protein
Gm2-Ap
Sphingolipid Activator Protein 3
Sap-3 Cleaved Into - Ganglioside Gm2 Activator Isoform Short
Database Links Reactome: R-HSA-6798695
Reactome: R-HSA-9840310
Cellular Localisation Lysosome
Alternative Antibody Names Anti-Ganglioside Gm2 Activator antibody
Anti-Cerebroside Sulfate Activator Protein antibody
Anti-Gm2-Ap antibody
Anti-Sphingolipid Activator Protein 3 antibody
Anti-Sap-3 Cleaved Into - Ganglioside Gm2 Activator Isoform Short antibody
Anti-GM2A antibody

Information sourced from Uniprot.org

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