| Tissue Specificity | Predominantly expressed in liver (at protein level) and kidney. Down-regulated in hepatocellular carcinoma and other liver cancers. |
| Function | Mitochondrial acyltransferase which transfers an acyl group to the N-terminus of glycine and glutamine, although much less efficiently. Can conjugate numerous substrates to form a variety of N-acylglycines, with a preference for benzoyl-CoA over phenylacetyl-CoA as acyl donors. Thereby detoxify xenobiotics, such as benzoic acid or salicylic acid, and endogenous organic acids, such as isovaleric acid. |
| Protein Name | Glycine N-AcyltransferaseAcyl-Coa -Glycine N-AcyltransferaseAacAralkyl Acyl-Coa N-AcyltransferaseAralkyl Acyl-Coa -Amino Acid N-AcyltransferaseBenzoyl-Coenzyme A -Glycine N-AcyltransferaseGlycine N-BenzoyltransferaseHrp-1(Clp |
| Database Links | Reactome: R-HSA-177128Reactome: R-HSA-177135Reactome: R-HSA-9749641 |
| Cellular Localisation | Mitochondrion |
| Alternative Antibody Names | Anti-Glycine N-Acyltransferase antibodyAnti-Acyl-Coa -Glycine N-Acyltransferase antibodyAnti-Aac antibodyAnti-Aralkyl Acyl-Coa N-Acyltransferase antibodyAnti-Aralkyl Acyl-Coa -Amino Acid N-Acyltransferase antibodyAnti-Benzoyl-Coenzyme A -Glycine N-Acyltransferase antibodyAnti-Glycine N-Benzoyltransferase antibodyAnti-Hrp-1(Clp antibodyAnti-GLYAT antibodyAnti-ACGNAT antibodyAnti-CAT antibodyAnti-GAT antibody |
Information sourced from Uniprot.org
