| Host: | Mouse |
| Applications: | ELISA/WB/ICC/IF/FACS |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal anti-Glutathione S-transferase pi 1/GSTP1 (1-210aa) for use in ELISA, WB, ICC, IF and FACS in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Monoclonal |
| Clone ID : | AT12C10 |
| Conjugation: | Unconjugated |
| Isotype: | IgG1k |
| Formulation: | Liquid in phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol |
| Purification: | By protein-A affinity chromatography |
| Concentration: | 1 mg/mL |
| Storage Instruction: | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | GSTP1 |
| Gene ID: | 2950 |
| Uniprot ID: | GSTP1_HUMAN |
| Immunogen Region: | 1-210aa |
| Accession Number: | NP_000843 |
| Immunogen: | Recombinant human GSTP1 (1-210aa) purified from E.coli. |
| Function | Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Involved in the formation of glutathione conjugates of both prostaglandin A2 (PGA2) and prostaglandin J2 (PGJ2). Participates in the formation of novel hepoxilin regioisomers. Negatively regulates CDK5 activity via p25/p35 translocation to prevent neurodegeneration. |
| Protein Name | Glutathione S-Transferase PGst Class-PiGstp1-1 |
| Database Links | Reactome: R-HSA-156590Reactome: R-HSA-3299685Reactome: R-HSA-6798695Reactome: R-HSA-9753281 |
| Cellular Localisation | CytoplasmMitochondrionNucleusThe 83 N-Terminal Amino Acids Function As Un Uncleaved Transit PeptideAnd Arginine Residues Within It Are Crucial For Mitochondrial Localization |
| Alternative Antibody Names | Anti-Glutathione S-Transferase P antibodyAnti-Gst Class-Pi antibodyAnti-Gstp1-1 antibodyAnti-GSTP1 antibodyAnti-FAEES3 antibodyAnti-GST3 antibody |
Information sourced from Uniprot.org