Anti-Glucose Transporter GLUT1 antibody [R09-7B8] (STJA0035715)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthesized peptide derived from human Glucose Transporter GLUT1
General Information
| Short Description | Rabbit monoclonal anti-Glucose Transporter GLUT1 for use in WB, IHC-P, ICC, IF and FC in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ICC/IF/FC |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R09-7B8 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Chromatography |
| Dilution Range | WB 1:500-1:1000IHC 1:50-1:100IF 1:50-1:200FC 1:50-1:100 |
| Formulation | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | SLC2A1 |
| Gene ID | 6513 |
| Uniprot ID | GTR1_HUMAN |
| Immunogen | A synthesized peptide derived from human Glucose Transporter GLUT1 |
Additional Info
| Tissue Specificity | Detected in erythrocytes (at protein level). Expressed at variable levels in many human tissues. |
| Post Translational Modifications | Phosphorylation at Ser-226 by PKC promotes glucose uptake by increasing cell membrane localization. |
| Function | Facilitative glucose transporter, which is responsible for constitutive or basal glucose uptake. Has a very broad substrate specificity.can transport a wide range of aldoses including both pentoses and hexoses. Most important energy carrier of the brain: present at the blood-brain barrier and assures the energy-independent, facilitative transport of glucose into the brain. In association with BSG and NXNL1, promotes retinal cone survival by increasing glucose uptake into photoreceptors. Required for mesendoderm differentiation. |
| Protein Name | Solute Carrier Family 2 - Facilitated Glucose Transporter Member 1Glucose Transporter Type 1 - Erythrocyte/BrainGlut-1Hepg2 Glucose Transporter |
| Database Links | Reactome: R-HSA-189200Reactome: R-HSA-196836Reactome: R-HSA-422356Reactome: R-HSA-5619043Reactome: R-HSA-5653890 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinMelanosomePhotoreceptor Inner SegmentLocalizes Primarily At The Cell SurfaceIdentified By Mass Spectrometry In Melanosome Fractions From Stage I To Stage Iv |
| Alternative Antibody Names | Anti-Solute Carrier Family 2 - Facilitated Glucose Transporter Member 1 antibodyAnti-Glucose Transporter Type 1 - Erythrocyte/Brain antibodyAnti-Glut-1 antibodyAnti-Hepg2 Glucose Transporter antibodyAnti-SLC2A1 antibodyAnti-GLUT1 antibody |
Information sourced from Uniprot.org