| Function | Together with BOLA2, acts as a cytosolic iron-sulfur (Fe-S) cluster assembly factor that facilitates 2Fe-2S cluster insertion into a subset of cytosolic proteins. Acts as a critical negative regulator of cardiac hypertrophy and a positive inotropic regulator. Required for hemoglobin maturation. Does not possess any thyoredoxin activity since it lacks the conserved motif that is essential for catalytic activity. |
| Protein Name | Glutaredoxin-3Pkc-Interacting Cousin Of ThioredoxinPicotPkc-Theta-Interacting ProteinPkcq-Interacting ProteinThioredoxin-Like Protein 2 |
| Database Links | Reactome: R-HSA-917937 |
| Cellular Localisation | CytoplasmCytosolCell CortexMyofibrilSarcomereZ LineUnder The Plasma MembraneAfter Pma StimulationGlrx3 And Prkcq/Pkc-Theta Translocate To A More Extended Submembrane AreaIn The Z LineFound Associated With Csrp3 |
| Alternative Antibody Names | Anti-Glutaredoxin-3 antibodyAnti-Pkc-Interacting Cousin Of Thioredoxin antibodyAnti-Picot antibodyAnti-Pkc-Theta-Interacting Protein antibodyAnti-Pkcq-Interacting Protein antibodyAnti-Thioredoxin-Like Protein 2 antibodyAnti-GLRX3 antibodyAnti-PICOT antibodyAnti-TXNL2 antibodyAnti-HUSSY-22 antibody |
Information sourced from Uniprot.org
