Anti-GK antibody (461-510 aa) (STJ93275)

SKU:
STJ93275
$67.62 - $360.18
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Short Description :Rabbit polyclonal anti-Glycerol kinase (461-510 aa) for use in WB, IF and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications:WB/IF/ELISA
Host:Rabbit
Reactivity:Human/Mouse/Rat
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Unconjugated
Concentration:1 mg/mL
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution Range:WB 1:500-1:2000
IF 1:200-1:1000
ELISA 1:20000
Formulation:Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:GK
Gene ID:2710
Uniprot ID:GLPK_HUMAN
Immunogen:The antiserum was produced against synthesized peptide derived from the human GK at the amino acid range 461-510
Immunogen Region:461-510 aa
Specificity:GK1 Polyclonal Antibody detects endogenous levels of GK1 protein.
Function Kinase that plays a key role in glycerol metabolism, catalyzing its phosphorylation to produce sn-glycerol 3-phosphate. Sn-glycerol 3-phosphate is a crucial intermediate in various metabolic pathways, such as the synthesis of glycerolipids and triglycerides, glycogenesis, glycolysis and gluconeogenesis.
Protein Name Glycerol Kinase
Glycerokinase
Atp -Glycerol 3-Phosphotransferase
Database Links Reactome: R-HSA-75109
Cellular Localisation Mitochondrion Outer Membrane
Single-Pass Membrane Protein
Nucleus
Cytoplasm
Cytosol
Glycerol Kinase Activity Is More Cytosolic In Some Tissues
It Probably Represents The Expression Of Isoforms Lacking A Transmembrane Domain
Isoform 3: Mitochondrion Outer Membrane
In Sperm And Fetal Tissues
The Majority Of The Activity Is Associated With Mitochondria
Isoform 4: Cytoplasm
In Adult Tissues
Such As Liver The Glycerol Kinase Activity Is More Cytosolic
It Probably Represents The Expression Of This Isoform Which Lacks A Transmembrane Domain
Alternative Antibody Names Anti-Glycerol Kinase antibody
Anti-Glycerokinase antibody
Anti-Atp -Glycerol 3-Phosphotransferase antibody
Anti-GK antibody

Information sourced from Uniprot.org