Anti-GITR antibody [ZN203] (STJA0033372)

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STJA0033372
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Host: Mouse
Applications: IHC-P
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Mouse monoclonal anti-GITR for use in IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents.
Clonality : Monoclonal
Clone ID : ZN203
Conjugation: Unconjugated
Isotype: IgG2b
Formulation: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification: Affinity Chromatography
Concentration: 0.5-1.0 mg/mL
Dilution Range: IHC 1:50-1:100
Storage Instruction: Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles.
Gene Symbol: TNFRSF18
Gene ID: 8784
Uniprot ID: TNR18_HUMAN
Immunogen: Human recombinant protein fragment of human TNFRSF18 (NP_004186) produced in E.coli.
Tissue Specificity Expressed in lymph node, peripheral blood leukocytes and weakly in spleen.
Function Receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway.
Protein Name Tumor Necrosis Factor Receptor Superfamily Member 18
Activation-Inducible Tnfr Family Receptor
Glucocorticoid-Induced Tnfr-Related Protein
Cd Antigen Cd357
Database Links Reactome: R-HSA-5669034
Reactome: R-HSA-8877330
Cellular Localisation Isoform 1: Cell Membrane
Single-Pass Type I Membrane Protein
Isoform 2: Secreted
Alternative Antibody Names Anti-Tumor Necrosis Factor Receptor Superfamily Member 18 antibody
Anti-Activation-Inducible Tnfr Family Receptor antibody
Anti-Glucocorticoid-Induced Tnfr-Related Protein antibody
Anti-Cd Antigen Cd357 antibody
Anti-TNFRSF18 antibody
Anti-AITR antibody
Anti-GITR antibody
Anti-UNQ319 antibody
Anti-PRO364 antibody

Information sourced from Uniprot.org

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