Anti-GITR antibody [DM78] (STJA0038110)

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STJA0038110-100
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Host: Rabbit
Applications: FC/ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit monoclonal anti-GITR for use in FC and ELISA in Human samples. Datasheet included with dilution recommendations, and related reagents.
Clonality : Monoclonal
Clone ID : DM78
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Purification: Affinity Chromatography
Dilution Range: FC 1:50-1:100
ELISA 1:10000
Storage Instruction: Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles.
Gene Symbol: TNFRSF18
Gene ID: 8784
Uniprot ID: TNR18_HUMAN
Immunogen: Recombinant human GITR protein
Tissue Specificity Expressed in lymph node, peripheral blood leukocytes and weakly in spleen.
Function Receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway.
Protein Name Tumor Necrosis Factor Receptor Superfamily Member 18
Activation-Inducible Tnfr Family Receptor
Glucocorticoid-Induced Tnfr-Related Protein
Cd Antigen Cd357
Database Links Reactome: R-HSA-5669034
Reactome: R-HSA-8877330
Cellular Localisation Isoform 1: Cell Membrane
Single-Pass Type I Membrane Protein
Isoform 2: Secreted
Alternative Antibody Names Anti-Tumor Necrosis Factor Receptor Superfamily Member 18 antibody
Anti-Activation-Inducible Tnfr Family Receptor antibody
Anti-Glucocorticoid-Induced Tnfr-Related Protein antibody
Anti-Cd Antigen Cd357 antibody
Anti-TNFRSF18 antibody
Anti-AITR antibody
Anti-GITR antibody
Anti-UNQ319 antibody
Anti-PRO364 antibody

Information sourced from Uniprot.org

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