• Western blot analysis of extracts of various cell lines, using GINS4 antibody (STJ111324) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% non-fat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.
  • Western blot analysis of extracts of various cell lines, using GINS4 antibody (STJ111324) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.

Anti-GINS4 antibody (108-207) (STJ111324)

SKU:
STJ111324

£112.50 - £522.50
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-GINS4 (108-207) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: GINS4
Gene ID: 84296
Uniprot ID: SLD5_HUMAN
Immunogen Region: 108-207
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 108-207 of human GINS4 (NP_115712.1).
Immunogen Sequence: LEKEKTRPEGEPSSLSPEEL AFAREFMANTESYLKNVALK HMPPNLQKVDLFRAVPKPDL DSYVFLRVRERQENILVEPD TDEQRDYVIDLEKGSQHLIR
Function Required for correct functioning of the GINS complex, a complex that plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex is a core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built.
Protein Name Dna Replication Complex Gins Protein Sld5
Gins Complex Subunit 4 Cleaved Into - Dna Replication Complex Gins Protein Sld5 - N-Terminally Processed
Database Links Reactome: R-HSA-176974
Cellular Localisation Nucleus
Chromosome
Cytoplasm
Associates With Chromatin
Alternative Antibody Names Anti-Dna Replication Complex Gins Protein Sld5 antibody
Anti-Gins Complex Subunit 4 Cleaved Into - Dna Replication Complex Gins Protein Sld5 - N-Terminally Processed antibody
Anti-GINS4 antibody
Anti-SLD5 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance