| Host: | Rabbit |
| Applications: | WB/ICC/IF/IP |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit monoclonal antibody anti-PSF1 (152-164 aa) is suitable for use in Western Blot, Immunocytochemistry, Immunofluorescence and Immunoprecipitation research applications. |
| Clonality : | Monoclonal |
| Clone ID : | R04-1A8 |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 50mM Tris-Glycine (pH7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Purification: | Affinity Purified |
| Concentration: | 0.3 mg/ml |
| Dilution Range: | WB 1:500-1:1000IF 1:50-1:200IP 1:20 |
| Storage Instruction: | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
| Gene Symbol: | GINS1 |
| Gene ID: | 9837 |
| Uniprot ID: | PSF1_HUMAN |
| Immunogen Region: | 152-164 aa |
| Immunogen: | A synthetic peptide of human PSF1 |
| Function | Required for correct functioning of the GINS complex, a complex that plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex is a core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built. |
| Protein Name | Dna Replication Complex Gins Protein Psf1Gins Complex Subunit 1 |
| Database Links | Reactome: R-HSA-176974 |
| Cellular Localisation | NucleusChromosomeAssociates With Chromatin |
| Alternative Antibody Names | Anti-Dna Replication Complex Gins Protein Psf1 antibodyAnti-Gins Complex Subunit 1 antibodyAnti-GINS1 antibodyAnti-KIAA0186 antibodyAnti-PSF1 antibody |
Information sourced from Uniprot.org