Anti-GIF antibody (20-300) (STJ28994)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal GIF (20-300) antibody for use in WB, IF, ICC and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IF/ICC:1:50-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CBLIF |
| Gene ID | 2694 |
| Uniprot ID | IF_HUMAN |
| Immunogen Region | 20-300 |
| Immunogen Sequence | TQTQSSCSVPSAQEPLVNGI QVLMENSVTSSAYPNPSILI AMNLAGAYNLKAQKLLTYQL MSSDNNDLTIGQLGLTIMAL TSSCRDPGDKVSILQRQMEN WAPSSPNAEASAFYGPSLAI LALCQKNSEATLPIAVRFAK TLLANSSPFNVDTGAMATLA LTCMYNKIPVGSEEGYRSLF GQVLKDIVEKISMKIKDNGI IGDIYSTGLAMQALSVTPEP SKKEWNCKKTTDMILNEIK |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 20-300 of human GIF (NP_005133.2). |
Additional Info
| Tissue Specificity | Gastric mucosa. |
| Function | Promotes absorption of the essential vitamin cobalamin (Cbl) in the ileum. After interaction with CUBN, the CBLIF-cobalamin complex is internalized via receptor-mediated endocytosis. |
| Protein Name | Cobalamin Binding Intrinsic FactorGastric Intrinsic FactorIntrinsic FactorIfInf |
| Database Links | Reactome: R-HSA-3359457Reactome: R-HSA-3359462Reactome: R-HSA-3359463Reactome: R-HSA-9758881 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Cobalamin Binding Intrinsic Factor antibodyAnti-Gastric Intrinsic Factor antibodyAnti-Intrinsic Factor antibodyAnti-If antibodyAnti-Inf antibodyAnti-CBLIF antibodyAnti-GIF antibodyAnti-IFMH antibody |
Information sourced from Uniprot.org