Western blot analysis of various lysates, using GFPT1 antibody (STJ23774) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% non-fat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.

Anti-GFPT1 antibody (1-150) (STJ23774)

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STJ23774
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:1000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: GFPT1
Gene ID: 2673
Uniprot ID: GFPT1_HUMAN
Immunogen Region: 1-150
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 1-150 of human GFPT1 (NP_002047.2).
Immunogen Sequence: MCGIFAYLNYHVPRTRREIL ETLIKGLQRLEYRGYDSAGV GFDGGNDKDWEANACKIQLI KKKGKVKALDEEVHKQQDMD LDIEFDVHLGIAHTRWATHG EPSPVNSHPQRSDKNNEFIV IHNGIITNYKDLKKFLESKG YDFESETDTE
Tissue Specificity Isoform 1 is predominantly expressed in skeletal muscle. Not expressed in brain. Seems to be selectively expressed in striated muscle.
Function Controls the flux of glucose into the hexosamine pathway. Most likely involved in regulating the availability of precursors for N- and O-linked glycosylation of proteins. Regulates the circadian expression of clock genes BMAL1 and CRY1. Has a role in fine tuning the metabolic fluctuations of cytosolic UDP-GlcNAc and its effects on hyaluronan synthesis that occur during tissue remodeling.
Protein Name Glutamine--Fructose-6-Phosphate Aminotransferase Isomerizing 1
D-Fructose-6-Phosphate Amidotransferase 1
Glutamine -Fructose-6-Phosphate Amidotransferase 1
Gfat 1
Gfat1
Hexosephosphate Aminotransferase 1
Database Links Reactome: R-HSA-381038
Reactome: R-HSA-4085023
Reactome: R-HSA-446210
Alternative Antibody Names Anti-Glutamine--Fructose-6-Phosphate Aminotransferase Isomerizing 1 antibody
Anti-D-Fructose-6-Phosphate Amidotransferase 1 antibody
Anti-Glutamine -Fructose-6-Phosphate Amidotransferase 1 antibody
Anti-Gfat 1 antibody
Anti-Gfat1 antibody
Anti-Hexosephosphate Aminotransferase 1 antibody
Anti-GFPT1 antibody
Anti-GFAT antibody
Anti-GFPT antibody

Information sourced from Uniprot.org

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