| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-GFPT1 (1-150) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:1000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
GFPT1 |
| Gene ID: |
2673 |
| Uniprot ID: |
GFPT1_HUMAN |
| Immunogen Region: |
1-150 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-150 of human GFPT1 (NP_002047.2). |
| Immunogen Sequence: |
MCGIFAYLNYHVPRTRREIL ETLIKGLQRLEYRGYDSAGV GFDGGNDKDWEANACKIQLI KKKGKVKALDEEVHKQQDMD LDIEFDVHLGIAHTRWATHG EPSPVNSHPQRSDKNNEFIV IHNGIITNYKDLKKFLESKG YDFESETDTE |
| Tissue Specificity | Isoform 1 is predominantly expressed in skeletal muscle. Not expressed in brain. Seems to be selectively expressed in striated muscle. |
| Function | Controls the flux of glucose into the hexosamine pathway. Most likely involved in regulating the availability of precursors for N- and O-linked glycosylation of proteins. Regulates the circadian expression of clock genes BMAL1 and CRY1. Has a role in fine tuning the metabolic fluctuations of cytosolic UDP-GlcNAc and its effects on hyaluronan synthesis that occur during tissue remodeling. |
| Protein Name | Glutamine--Fructose-6-Phosphate Aminotransferase Isomerizing 1D-Fructose-6-Phosphate Amidotransferase 1Glutamine -Fructose-6-Phosphate Amidotransferase 1Gfat 1Gfat1Hexosephosphate Aminotransferase 1 |
| Database Links | Reactome: R-HSA-381038Reactome: R-HSA-4085023Reactome: R-HSA-446210 |
| Alternative Antibody Names | Anti-Glutamine--Fructose-6-Phosphate Aminotransferase Isomerizing 1 antibodyAnti-D-Fructose-6-Phosphate Amidotransferase 1 antibodyAnti-Glutamine -Fructose-6-Phosphate Amidotransferase 1 antibodyAnti-Gfat 1 antibodyAnti-Gfat1 antibodyAnti-Hexosephosphate Aminotransferase 1 antibodyAnti-GFPT1 antibodyAnti-GFAT antibodyAnti-GFPT antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
