| Host: | Rabbit |
| Applications: | IHC/IF/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Growth/differentiation factor 2 (371-420 aa) is suitable for use in Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | IHC-P 1:50-200ELISA 1:10000-20000IF 1:50-200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | GDF2 |
| Gene ID: | 2658 |
| Uniprot ID: | GDF2_HUMAN |
| Immunogen Region: | 371-420 aa |
| Specificity: | The antibody detects endogenous BMP-9 |
| Immunogen: | Synthetic peptide from the human protein at the amino acid range 371-420 |
| Post Translational Modifications | A reversible disulfide bond can be formed between the two subunits in the homodimer.this has no effect on GDF2 activity. |
| Function | Potent circulating inhibitor of angiogenesis. Signals through the type I activin receptor ACVRL1 but not other Alks. Signaling through SMAD1 in endothelial cells requires TGF-beta coreceptor endoglin/ENG. |
| Protein Name | Growth/Differentiation Factor 2Gdf-2Bone Morphogenetic Protein 9Bmp-9 |
| Database Links | Reactome: R-HSA-201451 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Growth/Differentiation Factor 2 antibodyAnti-Gdf-2 antibodyAnti-Bone Morphogenetic Protein 9 antibodyAnti-Bmp-9 antibodyAnti-GDF2 antibodyAnti-BMP9 antibody |
Information sourced from Uniprot.org