Anti-GCAT antibody (170-419) (STJ118247)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal GCAT (170-419) antibody for use in WB, IHC-P, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IHC-P:1:50-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | GCAT |
| Gene ID | 23464 |
| Uniprot ID | KBL_HUMAN |
| Immunogen Region | 170-419 |
| Immunogen Sequence | KAHKYRYRHLDMADLEAKLQ EAQKHRLRLVATDGAFSMDG DIAPLQEICCLASRYGALVF MDECHATGFLGPTGRGTDEL LGVMDQVTIINSTLGKALGG ASGGYTTGPGPLVSLLRQRA RPYLFSNSLPPAVVGCASKA LDLLMGSNTIVQSMAAKTQR FRSKMEAAGFTISGASHPIC PVMLGDARLASRMADDMLKR GIFVIGFSYPVVPKGKARIR VQISAVHSEEDIDRCVEAF |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 170-419 of human GCAT (NP_055106.1). |
Additional Info
| Tissue Specificity | Strongly expressed in heart, brain, liver and pancreas. Also found in lung. |
| Function | Pyridoxal phosphate (PLP) dependent enzyme, which catalyzes the cleavage of 2-amino-3-oxobutanoate to glycine and acetyl-CoA. |
| Protein Name | 2-Amino-3-Ketobutyrate Coenzyme A Ligase - MitochondrialAkb LigaseAminoacetone SynthaseGlycine Acetyltransferase |
| Database Links | Reactome: R-HSA-8849175 |
| Cellular Localisation | MitochondrionNucleusTranslocates To The Nucleus Upon Cold And Osmotic Stress |
| Alternative Antibody Names | Anti-2-Amino-3-Ketobutyrate Coenzyme A Ligase - Mitochondrial antibodyAnti-Akb Ligase antibodyAnti-Aminoacetone Synthase antibodyAnti-Glycine Acetyltransferase antibodyAnti-GCAT antibodyAnti-KBL antibody |
Information sourced from Uniprot.org