| Short Description : | Rabbit polyclonal anti-Guanylate-binding protein 4 (551-600 aa) for use in WB, IHC, IF and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IHC/IF/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-1:2000IHC 1:100-1:300ELISA 1:40000IF 1:50-200 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | GBP4 |
| Gene ID: | 115361 |
| Uniprot ID: | GBP4_HUMAN |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human GBP4 at the amino acid range 551-600 |
| Immunogen Region: | 551-600 aa |
| Specificity: | GBP4 Polyclonal Antibody detects endogenous levels of GBP4 protein. |
| Function | Interferon (IFN)-inducible GTPase that plays important roles in innate immunity against a diverse range of bacterial, viral and protozoan pathogens. Negatively regulates the antiviral response by inhibiting activation of IRF7 transcription factor. |
| Protein Name | Guanylate-Binding Protein 4Gtp-Binding Protein 4Gbp-4Guanine Nucleotide-Binding Protein 4 |
| Database Links | Reactome: R-HSA-877300 |
| Cellular Localisation | Golgi Apparatus MembraneCytoplasmNucleusPerinuclear RegionHeterodimers With Gbp1Gbp2 And Gbp5 Localize In The Compartment Of The Prenylated Gbps: With Gbp1 In A Vesicle-Like CompartmentWith Gbp2Around The Nucleus And With Gbp5At The Golgi Apparatus |
| Alternative Antibody Names | Anti-Guanylate-Binding Protein 4 antibodyAnti-Gtp-Binding Protein 4 antibodyAnti-Gbp-4 antibodyAnti-Guanine Nucleotide-Binding Protein 4 antibodyAnti-GBP4 antibody |
Information sourced from Uniprot.org
