• Western blot of mouse whole brain lysates showing specific immunolabeling of the ~55 kDa Beta 1-subunit of the GABAA-R.

Anti-GABRB1 antibody (Cytoplasmic Loop) (STJA0003645)

SKU:
STJA0003645-100

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Host: Rabbit
Applications: WB
Reactivity: Mouse/Rat/Bovine/Canine/Chicken/Human/Non-Human Primates/Xenopus/Zebrafish
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-GABAA Receptor b1 (Cytoplasmic Loop) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 100 µl in 10 mM HEPES (pH 7.5) , 150 mM NaCl, 100 µg per ml BSA and 50% Glycerol.
Purification: This antibody was antigen affinity purified from pooled serum.
Dilution Range: WB 1:1000
IHC
ICC
IP
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: Gabrb1
Gene ID: 25450
Uniprot ID: GBRB1_RAT
Immunogen Region: Cytoplasmic Loop
Immunogen: Fusion protein from the cytoplasmic loop of the beta 1 subunit.
Function Component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the vertebrate brain. Functions also as histamine receptor and mediates cellular responses to histamine. Functions as receptor for diazepines and various anesthetics, such as pentobarbital.these are bound at a separate allosteric effector binding site. Functions as ligand-gated chloride channel.
Protein Name Gamma-Aminobutyric Acid Receptor Subunit Beta-1
Gaba(A Receptor Subunit Beta-1
Database Links Reactome: R-RNO-977443
Cellular Localisation Postsynaptic Cell Membrane
Multi-Pass Membrane Protein
Cell Membrane
Alternative Antibody Names Anti-Gamma-Aminobutyric Acid Receptor Subunit Beta-1 antibody
Anti-Gaba(A Receptor Subunit Beta-1 antibody
Anti-Gabrb1 antibody
Anti-Gabrb-1 antibody

Information sourced from Uniprot.org

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