| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | FXYD6 |
| Gene ID: | 53826 |
| Uniprot ID: | FXYD6_HUMAN |
| Immunogen Region: | 1-95 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-95 of human FXYD6 (NP_071286.1). |
| Immunogen Sequence: | MELVLVFLCSLLAPMVLASA AEKEKEMDPFHYDYQTLRIG GLVFAVVLFSVGILLILSRR CKCSFNQKPRAPGDEEAQVE NLITANATEPQKAEN |
| Function | Associates with and regulates the activity of the sodium/potassium-transporting ATPase (NKA) which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Reduces the apparent affinity for intracellular Na(+) with no change in the apparent affinity for extracellular K(+). In addition to modulating NKA kinetics, may also function as a regulator of NKA localization to the plasma membrane. |
| Protein Name | Fxyd Domain-Containing Ion Transport Regulator 6Phosphohippolin |
| Database Links | Reactome: R-HSA-5578775Reactome: R-HSA-936837Reactome: R-HSA-9679191 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Fxyd Domain-Containing Ion Transport Regulator 6 antibodyAnti-Phosphohippolin antibodyAnti-FXYD6 antibodyAnti-UNQ521 antibodyAnti-PRO1056 antibody |
Information sourced from Uniprot.org