• Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using FXR2 Antibody. The picture on the right is blocked with the synthesized peptide.
  • Western blot analysis of lysates from COLO205 cells, using FXR2 Antibody. The lane on the right is blocked with the synthesized peptide.
  • Immunofluorescence analysis of A549 cells, using FXR2 Antibody. The picture on the right is blocked with the synthesized peptide.

Anti-FXR2 antibody (551-600 aa) (STJ93168)

SKU:
STJ93168

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-RNA-binding protein FXR2 (551-600 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:10000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: FXR2
Gene ID: 9513
Uniprot ID: FXR2_HUMAN
Immunogen Region: 551-600 aa
Specificity: FXR2 Polyclonal Antibody detects endogenous levels of FXR2 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human FXR2 at the amino acid range 551-600
Function mRNA-binding protein that acts as a regulator of mRNAs translation and/or stability, and which is required for adult hippocampal neurogenesis. Specifically binds to AU-rich elements (AREs) in the 3'-UTR of target mRNAs. Promotes formation of some phase-separated membraneless compartment by undergoing liquid-liquid phase separation upon binding to AREs-containing mRNAs: mRNAs storage into membraneless compartments regulates their translation and/or stability. Acts as a regulator of adult hippocampal neurogenesis by regulating translation and/or stability of NOG mRNA, thereby preventing NOG protein expression in the dentate gyrus.
Protein Name Rna-Binding Protein Fxr2
Fxr2p
Fmr1 Autosomal Homolog 2
Cellular Localisation Cytoplasm
Cytoplasmic Ribonucleoprotein Granule
Postsynapse
Specifically Localizes To Cytoplasmic Ribonucleoprotein Membraneless Compartments
Localization To The Post-Synaptic Region Is Dependent On Fmr1
Alternative Antibody Names Anti-Rna-Binding Protein Fxr2 antibody
Anti-Fxr2p antibody
Anti-Fmr1 Autosomal Homolog 2 antibody
Anti-FXR2 antibody
Anti-FMR1L2 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance